Front Cover Picture: Recent Advances in Synthesis of Difluoromethylene Phosphonates for Biological Applications (Adv. Synth. Catal. 12/2021)

The front cover picture, designed by Michael Shevchuk, illustrates difluoromethylene phosphonates as bioisosteric, non-hydrolyzable analogs of natural phosphates, reflecting on their prominence molecular tools to study intricate phosphate biochemistry and beyond. review comprehensively summarizes the recent synthetic advances in chemistry phosphonates, such visible light-driven photocatalytic transformations, highlights compounds that have found significant importance biochemical research. Details can be Review Gerd-Volker Röschenthaler, Jianlin Han, co-workers (M. Q. Wang, R. Pajkert, J. Xu, H. Mei, G.-V. Adv. Synth. Catal. 2021, 363, 2912–2968; DOI: 10.1002/adsc.202001464).